Article
Apolipoprotein A5 T-1131C variant confers risk for metabolic syndrome.
Pathology oncology research : POR - 1 Jan 2007
Maász Anita, Kisfali Péter, Horvatovich Katalin, Mohás Márton, Markó Lajos, Csöngei Veronika, Faragó Bernadett, Járomi Luca, Magyari Lili, Sáfrány Enikô, Sipeky Csilla, Wittmann István, Melegh Béla
Abstract excerpt
The -1131C is a naturally occurring variant of the apolipoprotein A5 (ApoA5) gene, which has been shown to associate with increased triglyceride levels. This variant has also been shown to confer risk for development of ischemic heart disease and stroke. The gene is in linkage disequilibrium with factors known to correlate with impaired glucose homeostasis. These observations prompted us to study the prevalence...
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