Article
TolC, an Escherichia coli outer membrane protein required for hemolysin secretion.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990
Wandersman C, Delepelaire P
Abstract excerpt
Secretion of Escherichia coli alpha-hemolysin into the medium does not require the cleavage of an N-terminal signal peptide. The specific secretion apparatus was shown to consist of two proteins, HlyB and HlyD, both located in the inner membrane and encoded by genes contiguous to the hemolysin structural gene (hlyA). It was proposed that these two proteins constitute a membrane-bound translocator for hemolysin...
Topics
- Bacterial Outer Membrane Proteins
- Cell Membrane
- Coliphages
- Escherichia coli
- Genotype
- Hemolysin Proteins
- Mutation
- Phenotype
- Plasmids
- beta-Galactosidase
- beta-Lactamases