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Article

In vivo proteolytic degradation of the Escherichia coli acyltransferase HlyC.

The Journal of biological chemistry - 18 May 2001

Guzman-Verri C, Chaves-Olarte E, García F, Arvidson S, Moreno E

Abstract excerpt

Escherichia coli hemolysin (HlyA) is the prototype toxin of a major family of exoproteins produced by Gram-negative bacteria known as "repeats in toxins." Only fatty acid-acylated HlyA molecules at residues Lys564 and Lys690 are able to damage the target cell membrane. Fatty acylation of pro-HlyA is dependent on the co-synthesized acyltransferase HlyC and the acylated form of acyl-carrier protein. By using a...

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Source

Identifiers

PMID: 11278516
DOI: 10.1074/jbc.M009514200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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