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Article

Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans.

Science (New York, N.Y.) - 17 Dec 2010

Gallo Christopher M, Wang Jennifer T, Motegi Fumio, Seydoux Geraldine

Abstract excerpt

Asymmetric segregation of P granules during the first four divisions of the Caenorhabditis elegans embryo is a classic example of cytoplasmic partitioning of germline determinants. It is thought that asymmetric partitioning of P granule components during mitosis is essential to distinguish germline from soma. We have identified a mutant (pptr-1) in which P granules become unstable during mitosis and P granule...

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Identifiers

PMID: 21127218
DOI: 10.1126/science.1193697
PMCID: PMC3072820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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