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Article

Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2).

The Journal of biological chemistry - 11 Feb 2011

Vasanth Shivakumar, ZeRuth Gary, Kang Hong Soon, Jetten Anton M

Abstract excerpt

Gli-similar 1-3 (Glis1-3) constitute a subfamily of Krüppel-like zinc finger (ZF) transcription factors that are closely related to the Gli protein family. Mutations in GLIS2 are linked to nephronophthisis, a chronic kidney disease characterized by renal fibrosis and atrophy in children and young adults. Currently, very little information exists about the mechanism of action of Glis2, its target genes, or the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Zinc Finger Protein GLI1

Source

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Identifiers

PMID: 21127075
DOI: 10.1074/jbc.M110.165951
PMCID: PMC3039324

Genes

GLIS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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