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The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers.

Archivum immunologiae et therapiae experimentalis - 1 Oct 2017

Chou Chon-Kit, Tang Chin-Ju, Chou Han-Lin, Liu Chun-Yen, Ng Ming-Chong, Chang Yu-Ting, Yuan Shyng-Shiou F, Tsai Eing-Mei, Chiu Chien-Chih

Abstract excerpt

Gli-similar 3 (Glis3) belongs to a Glis subfamily of Krüppel-like zinc-finger transcription factors characterized to regulate a set of downstream targets essential for cellular functions, including pancreatic development, β-cell maturation and maintenance, and insulin production. Examination of the DNA-binding domain of Glis3 reveals that this domain contains a repeated cysteine 2/histidine 2 (Cys2/His2)...

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PMID: 28523428
DOI: 10.1007/s00005-017-0470-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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