Article
Immune modulation exerted by thymic humoral factor (THF-gamma 2), on T-cell subsets and IL-2 production of umbilical cord blood lymphocytes.
Immunopharmacology and immunotoxicology - 1 Jan 1990
Ben-Hur H, Pecht M, Netzer L, Borenstein R, Blickstein I, Burstein Y, Trainin N
Abstract excerpt
The effect of a synthetic thymic humoral factor, THF-gamma 2, on the immune competence of T-cells was investigated in vitro on lymphocytes from human cord blood (UCBL). It was found that preincubation of UCBL with THF-gamma 2 caused an increase in the percentage of cells expressing the CD4 or the CD8 differentiation antigens, but did not affect the percentage of CD3 cells. The effect of THF-gamma 2 on PHA-induced...
Topics
- Antigens, Differentiation, T-Lymphocyte
- CD4 Antigens
- CD8 Antigens
- Fetal Blood
- Humans
- Immunocompetence
- In Vitro Techniques
- Infant, Newborn
- Interleukin-2
- Lymphocytes