Article
Proliferative and cytotoxic responses of human cord blood T lymphocytes following allogeneic stimulation.
Cellular immunology - 1 Mar 1994
Risdon G, Gaddy J, Stehman F B, Broxmeyer H E
Abstract excerpt
On the basis of the success of recent cord blood transplants, we undertook a comparison of the proliferative and cytotoxic potential, following allogeneic stimulation, of E-rosetted T cells from cord blood or adult peripheral blood (PB3) or bone marrow (BM). The magnitude of the proliferative response of cord blood (CB) T cells to alloantigen was greater than or equal to that of adult PB or BM T cells....
Topics
- Adult
- Bone Marrow Transplantation
- Cytokines
- Cytotoxicity, Immunologic
- Female
- Fetal Blood
- Humans
- In Vitro Techniques
- Infant, Newborn
- Interferon-gamma
- Interleukin-2