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Article

IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium.

PloS one - 23 Nov 2010

Songhet Pascal, Barthel Manja, Röhn Till A, Van Maele Laurye, Cayet Delphine, Sirard Jean-Claude, Bachmann Martin, Kopf Manfred, Hardt Wolf-Dietrich

Abstract excerpt

Salmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes diarrhea and acute inflammation of the intestinal mucosa. The pro-inflammatory cytokines IL-17A and IL-17F are strongly induced in the infected mucosa but their contribution in driving the tissue inflammation is not understood. We have used the streptomycin mouse model to analyze the role of IL-17A and IL-17F and their cognate receptor...

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Identifiers

PMID: 21124903
DOI: 10.1371/journal.pone.0013804
PMCID: PMC2990720

Genes

CCL3
CCL4
CXCL1
CXCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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