Article
Anti-glomerular basement membrane disease: variant forms and underlying mechanisms.
Kidney international - 1 Aug 2026
Kuang Huang, Lin Cai-Xia, Jia Xiao-Yu, Cui Zhao, Borza Dorin-Bogdan, Zhao Ming-Hui
Abstract excerpt
Anti-glomerular basement membrane (GBM) disease is the most severe form of autoimmune glomerulonephritis following assaults on kidney and alveolar basement membranes by pathogenic anti-GBM antibodies. Typically, anti-GBM disease is characterized by rapidly progressive glomerulonephritis and an increased risk of lung hemorrhage, with kidney biopsy revealing ominous crescent formation. Although patient survival has...
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