Article
Single-gene testing combined with single nucleotide polymorphism microarray preimplantation genetic diagnosis for aneuploidy: a novel approach in optimizing pregnancy outcome.
Fertility and sterility - 1 Apr 2011
Brezina Paul R, Benner Andrew, Rechitsky Svetlana, Kuliev Anver, Pomerantseva Ekaterina, Pauling Dana, Kearns William G
Abstract excerpt
OBJECTIVE: To describe a method of amplifying DNA from blastocyst trophectoderm cells (two or three cells) and simultaneously performing 23-chromosome single nucleotide polymorphism microarrays and single-gene preimplantation genetic diagnosis. DESIGN: Case report. SETTING: IVF clinic and preimplantation genetic diagnostic centers. PATIENT(S): A 36-year-old woman, gravida 2, para 1011, and her husband who both...
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