Haplotype inference from short sequence reads using a population genealogical history model.

doi:10.1142/9789814335058_0030

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Article

Haplotype inference from short sequence reads using a population genealogical history model.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2011

Zhang Jin, Wu Yufeng

Abstract excerpt

High-throughput sequencing is currently a major transforming technology in biology. In this paper, we study a population genomics problem motivated by the newly available short reads data from high-throughput sequencing. In this problem, we are given short reads collected from individuals in a population. The objective is to infer haplotypes with the given reads. We first formulate the computational problem of...

Topics

Algorithms
Computational Biology
Genealogy and Heraldry
Genetics, Population
Haplotypes
High-Throughput Nucleotide Sequencing
Humans
Models, Genetic
Polymorphism, Single Nucleotide
Recombination, Genetic
Software

Source

Open in PubMed

Identifiers

PMID: 21121056
DOI: 10.1142/9789814335058_0030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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