Article
An assembly-free method of phylogeny reconstruction using short-read sequences from pooled samples without barcodes.
PLoS computational biology - 1 Sept 2021
Wong Thomas K F, Li Teng, Ranjard Louis, Wu Steven H, Sukumaran Jeet, Rodrigo Allen G
Abstract excerpt
A current strategy for obtaining haplotype information from several individuals involves short-read sequencing of pooled amplicons, where fragments from each individual is identified by a unique DNA barcode. In this paper, we report a new method to recover the phylogeny of haplotypes from short-read sequences obtained using pooled amplicons from a mixture of individuals, without barcoding. The method, AFPhyloMix,...
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