Article
A conserved motif at the C terminus of sororin is required for sister chromatid cohesion.
The Journal of biological chemistry - 4 Feb 2011
Wu Frank M, Nguyen Judy V, Rankin Susannah
Abstract excerpt
Sororin is a positive regulator of sister chromatid cohesion that interacts with the cohesin complex. Sororin is required for the increased stability of the cohesin complex on chromatin following DNA replication and sister chromatid cohesion during G(2). The mechanism by which sororin ensures cohesion is currently unknown. Because the primary sequence of sororin does not contain any previously characterized...
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