Article
EphB signaling controls lineage plasticity of adult neural stem cell niche cells.
Cell stem cell - 3 Dec 2010
Nomura Tadashi, Göritz Christian, Catchpole Timothy, Henkemeyer Mark, Frisén Jonas
Abstract excerpt
Stem cells remain in specialized niches over the lifespan of the organism in many organs to ensure tissue homeostasis and enable regeneration. How the niche is maintained is not understood, but is probably as important as intrinsic stem cell self-renewal capacity for tissue integrity. We here demonstrate a high degree of phenotypic plasticity of the two main niche cell types, ependymal cells and astrocytes, in...
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