Article
The impact of general intellectual ability and white matter volume on the functional outcome of patients with Bipolar Disorder and their relatives.
Journal of affective disorders - 1 May 2011
Forcada Irene, Papachristou Efstathios, Mur Maria, Christodoulou Tessa, Jogia Jigar, Reichenberg Abraham, Vieta Eduard, Frangou Sophia
Abstract excerpt
BACKGROUND: There is substantial evidence that cognitive deficits and brain structural abnormalities are present in patients with Bipolar Disorder (BD) and in their first-degree relatives. Previous studies have demonstrated associations between cognition and functional outcome in BD patients but have not examined the role of brain morphological changes. Similarly, the functional impact of either cognition or...
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