Article
Quantitative and phenotypic analyses of lymphocyte-monocyte heterokaryons induced by the HIV envelope proteins: Significant loss of lymphoid markers.
Experimental and molecular pathology - 1 Apr 2011
Rivera-Toledo Evelyn, Huerta Leonor, Larralde Carlos, Lamoyi Edmundo
Abstract excerpt
Cells infected with the human immunodeficiency virus (HIV) can fuse with CD4(+) cells leading to the formation of multinucleated cells. The presence of multinucleated cells infected with HIV in tissues of patients has been documented, although their cellular composition and role in AIDS pathogenesis is still under study. Here, we present evidence of in vitro heterotypic lymphocyte-monocyte fusion in cocultures of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.