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Article

De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.

PloS one - 1 Jan 2012

Gartner Suzanne, Liu Yiling, Natesan Senthilkumar

Abstract excerpt

Nurse cells are defined as those that provide for the development of other cells. We report here, that in vitro, human monocyte-derived macrophages can behave as nurse cells with functional capabilities that include de novo generation of CD4+ T-lymphocytes and a previously unknown small cell with monocytoid characteristics. We named these novel cells "self-renewing monocytoid cells" (SRMC), because they could...

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Identifiers

PMID: 22911696
DOI: 10.1371/journal.pone.0040139
PMCID: PMC3399863

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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