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Article

New horizons in the treatment of cystic fibrosis.

British journal of pharmacology - 1 May 2011

Cuthbert A W

Abstract excerpt

Cystic fibrosis (CF) is a lethal, recessive, genetic disease affecting approximately 1 in 2500 live births among Caucasians. The CF gene codes for a cAMP/PKA-dependent, ATP-requiring, membrane chloride ion channel, generally found in the apical membranes of many secreting epithelia and known as CFTR (cystic fibrosis transmembrane conductance regulator). There are currently over 1700 known mutations affecting...

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Source

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Identifiers

PMID: 21108631
DOI: 10.1111/j.1476-5381.2010.01137.x
PMCID: PMC3085876

Genes

CFTR
ASL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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