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Article

Inhibition of Enveloped Virus Infection of Cultured Cells by Valproic Acid

25 Nov 2010

Abstract excerpt

Valproic acid (VPA) is a short-chain fatty acid commonly used for treatment of neurological disorders. As VPA can interfere with cellular lipid metabolism, its effect on the infection of cultured cells by viruses of seven viral families relevant to human and animal health, including eight enveloped and four nonenveloped viruses, was analyzed. VPA drastically inhibited multiplication of all the enveloped viruses...

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PMID: 21106740
DOI: 10.1128/jvi.01717-10

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