Article
Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Dec 2010
Clifford Robert J, Zhang Jinghui, Meerzaman Daoud M, Lyu Myung-Soo, Hu Ying, Cultraro Constance M, Finney Richard P, Kelley Jenny M, Efroni Sol, Greenblum Sharon I, Nguyen Cu V, Rowe William L, Sharma Sweta, Wu Gang, Yan Chunhua, Zhang Hongen, Chung Young-Hwa, Kim Jeong A, Park Neung Hwa, Song Il Han, Buetow Kenneth H
Abstract excerpt
UNLABELLED: Primary liver cancer is the third most common cause of cancer-related death worldwide, with a rising incidence in Western countries. Little is known about the genetic etiology of this disease. To identify genetic factors associated with hepatocellular carcinoma (HCC) and liver cirrhosis (LC), we conducted a comprehensive, genome-wide variation analysis in a population of unrelated Asian individuals....
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