Article
Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2011
Garcia-Albeniz Xabier, Pericay Carles, Alonso-Espinaco Virginia, Alonso Vicente, Escudero Pilar, Fernández-Martos Carlos, Gallego Rosa, Gascón Pere, Castellví-Bel Sergi, Maurel Joan
Abstract excerpt
The purpose of the study was to prospectively explore the role of serum MMP-7 as a predictive and prognostic marker of anti-epidermal growth factor receptor (EGFR) therapy and irinotecan efficacy in third-line advanced colorectal cancer therapy. One hundred patients were recruited prospectively f...
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