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Article

Single-copy gain of chromosome 1q is a negative prognostic marker in pediatric nonependymal, nonpilocytic gliomas.

Neurosurgery - 1 Jan 2011

Miwa Tomoru, Hirose Yuichi, Sasaki Hikaru, Ezaki Taketo, Yoshida Kazunari, Kawase Takeshi

Abstract excerpt

BACKGROUND: Reports of genetic analyses on pediatric gliomas are few, and those tumors have been far less characterized than adult gliomas. OBJECTIVE: To characterize the genetic and biological features of pediatric gliomas. METHODS: We investigated 23 pediatric nonependymal, nonpilocytic gliomas for chromosomal copy number aberrations (CNAs) by comparative genomic hybridization (CGH), mutations of isocitrate...

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Source

Identifiers

PMID: 21099717
DOI: 10.1227/NEU.0b013e3181fd2c2e

Genes

MGMT
IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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