<i>Helicobacter pylori</i> proinflammatory protein up-regulates NF-κB as a cell-translocating Ser/Thr kinase

Abstract excerpt

There has been considerable interest in virulence genes in the plasticity region of Helicobacter pylori, but little is known about many of these genes. JHP940, one of the virulence factors encoded by the plasticity region of H. pylori strain J99, is a proinflammatory protein that induces tumor necrosis factor-alpha and interleukin-8 secretion as well as enhanced translocation of NF-κB in cultured macrophages....

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