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Article

Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2011

van der Veldt Astrid A M, Eechoute Karel, Gelderblom Hans, Gietema Jourik, Guchelaar Henk-Jan, van Erp Nielka P, van den Eertwegh Alfons J M, Haanen John B, Mathijssen Ron H J, Wessels Judith A M

Abstract excerpt

PURPOSE: The objective of this study was to identify genetic polymorphisms related to the pharmacokinetics and pharmacodynamics of sunitinib that are associated with a prolonged progression-free survival (PFS) and/or overall survival (OS) in patients with clear-cell metastatic renal cell cancer (...

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Source

Identifiers

PMID: 21097692
DOI: 10.1158/1078-0432.CCR-10-1828

Genes

ABCB1
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21097692-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib.PMID 21097692Read ↗

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