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Article

Chromosomal aberrations in railroad transit workers: effect of genetic polymorphisms.

Environmental and molecular mutagenesis - 1 May 2009

Catalán Julia, Heilimo Iiris, Falck Ghita C-M, Järventaus Hilkka, Rosenström Päivi, Nykyri Erkki, Kallas-Tarpila Tarja, Pitkämäki Leena, Hirvonen Ari, Norppa Hannu

Abstract excerpt

Complex chemical mixtures are transported by train from Russia to Finland for further shipment. Here, we studied if exposure to genotoxic components among these substances could affect chromosomal aberrations (CAs) in peripheral lymphocytes of workers handling the tank cars. An initial survey among 48 railroad workers and 39 referents (male smokers and nonsmokers) showed an elevation of CAs. A campaign was...

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Source

Identifiers

PMID: 19177501
DOI: 10.1002/em.20458

Genes

MTHFR
EPHX1
ERCC2
MTR
NAT2
XRCC1
XRCC3
ERCC5
GSTM1
GSTP1
GSTT1
NAT1
XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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