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Article

Mutational and promoter hypermethylation status of FHIT gene in breast cancer patients of Kashmir.

Mutation research - 10 Feb 2011

Syeed Nidda, Husain Syed Akhtar, Sameer A Syed, Chowdhri Nissar A, Siddiqi Mushtaq A

Abstract excerpt

OBJECTIVE: Fragile histidine triad (FHIT) gene located at chromosome 3p14.2 is a putative tumor suppressor gene involved in the pathogenesis of breast cancer. Both genetic and epigenetic alterations in FHIT have been implicated in breast carcinoma. In the present study, our main aim was to study...

Read the complete abstract on PubMed

Topics

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Share to Acid Anhydride Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, Tumor Suppressor

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 21095196
DOI: 10.1016/j.mrfmmm.2010.11.001

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21095196-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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