Article
Adhesion molecules expression in CLL: Potential impact on clinical and hematological parameters.
Journal of the Egyptian National Cancer Institute - 1 Mar 2016
Kamel Azza M, El-Sharkawy Nahla M, Osman Randa A, Abd El-Fattah Eman K, El-Noshokaty Essam, Abd El-Hamid Thoraya, Kandeel Eman Z
Abstract excerpt
BACKGROUND: B-cell chronic lymphocytic leukemia (CLL) is marked by the accumulation of CD5+ B lymphocytes within the blood, bone marrow (BM), and secondary lymphoid tissues. Abnormalities in the expression and function of cell adhesion molecules may account for the patterns of intra-nodal growth and hematogenous spread of the malignant cells. Chemokines and integrin-mediated adhesion and trans-endothelial...
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