Article
Association of vascular endothelial growth factor -2578C/A gene polymorphism in Chinese patients with colon cancer.
Genetic testing and molecular biomarkers - 1 Mar 2011
Zhang Lin, Zhang Guohu, Wang Peihong, Gong Jiaqing, Cao Yongkuan, Tang Lijun
Abstract excerpt
The vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in the process of angiogenesis, a crucial phase in tumor growth and metastasis. We carried out a case-control study to evaluate whether VEGF -2578C/A gene polymorphism modulates the risk of developing colon cancer. A total of 110 colon cancer patients and 110 cancer-free healthy people were recruited in the Chinese...
Topics
- Aged
- Asian People
- Case-Control Studies
- Colonic Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
