Article
[Polymorphic variants of folate metabolizing genes (C677T and A1298C MTHFR, C1420T SHMT1 and G1958A MTHFD) are not associated with the risk of breast cancer in West Siberian Region of Russia].
Molekuliarnaia biologiia - 1 Jan 2000
Vaĭner A S, Boiarskikh U A, Voronina E N, Selezneva I A, Sinkina T V, Lazarev A F, Petrova V D, Filipenko M L
Abstract excerpt
Breast cancer is the most incident cancer among women. We investigated the role of polymorphisms of folate metabolizing genes MTHFR (C677T and A1298C), SHMT1 (C1420T) and MTHFD (G1258A) in genetic susceptibility to this type of cancer. We determined allele and genotype frequencies in case (850 wo...
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