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Article

Variants of the adenosine A(2A) receptor gene are protective against proliferative diabetic retinopathy in patients with type 1 diabetes.

Ophthalmic research - 1 Jan 2011

Charles Bashira A, Conley Yvette P, Chen Guanjie, Miller Rachel G, Dorman Janice S, Gorin Michael B, Ferrell Robert E, Sereika Susan M, Rotimi Charles N, Orchard Trevor J

Abstract excerpt

AIMS: The adenosine A(2A) receptor (ADORA(2A)) may ameliorate deleterious physiologic effects associated with tissue injury in individuals with diabetes. We explored associations between variants of the ADORA(2A) gene and proliferative diabetic retinopathy (PDR) in a cohort of patients with type 1 diabetes (T1D). METHODS: The participants were from the Pittsburgh Epidemiology of Diabetes Complications prospective...

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Share to Diabetes Mellitus, Type 1
Share to Diabetic Retinopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Receptor, Adenosine A2A

Share to Retinal Neovascularization

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 21088442
DOI: 10.1159/000317057
PMCID: PMC2997447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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