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Article

Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2011

Findeisen Hannes M, Gizard Florence, Zhao Yue, Cohn Dianne, Heywood Elizabeth B, Jones Karrie L, Lovett David H, Howatt Deborah A, Daugherty Alan, Bruemmer Dennis

Abstract excerpt

OBJECTIVE: Abdominal aortic aneurysms (AAA) are an age-related vascular disease and an important cause of morbidity and mortality. In this study, we sought to determine whether the catalytic component of telomerase, telomerase reverse transcriptase (TERT), modulates angiotensin (Ang) II-induced AAA formation. METHODS AND RESULTS: Low-density lipoprotein receptor-deficient (LDLr-/-) mice were lethally irradiated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21088250
DOI: 10.1161/ATVBAHA.110.218545
PMCID: PMC3025410

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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