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Article

Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.

The Biochemical journal - 15 Feb 2011

Calvo Ana C, Pey Angel L, Miranda-Vizuete Antonio, Døskeland Anne P, Martinez Aurora

Abstract excerpt

TH (tyrosine hydroxylase) is the rate-limiting enzyme in the synthesis of catecholamines. The cat-2 gene of the nematode Caenorhabditis elegans is expressed in mechanosensory dopaminergic neurons and has been proposed to encode a putative TH. In the present paper, we report the cloning of C. eleg...

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Source

Identifiers

PMID: 21087208
DOI: 10.1042/BJ20101561

Genes

CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21087208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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