Article
Methylation analysis of the NOTCH4 -25 C/T polymorphism in schizophrenia.
Psychiatric genetics - 1 Feb 2011
McDonald Patrick P, O'reilly Richard, Singh Shiva M
Abstract excerpt
BACKGROUND: The major histocompatability complex on chromosome 6p has often been identified as containing potential risk factors for schizophrenia. The NOTCH4 gene is located within this region (6p21.3) and sequence variants have previously shown association to the disease. It is further implicated from a functional standpoint as it plays a critical role during the neurodevelopmental process. METHODS: This...
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