Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.

doi:10.1093/hmg/ddq497

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Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.

Human molecular genetics - 1 Feb 2011

Saad Mohamad, Lesage Suzanne, Saint-Pierre Aude, Corvol Jean-Christophe, Zelenika Diana, Lambert Jean-Charles, Vidailhet Marie, Mellick George D, Lohmann Ebba, Durif Franck, Pollak Pierre, Damier Philippe, Tison François, Silburn Peter A, Tzourio Christophe, Forlani Sylvie, Loriot Marie-Anne, Giroud Maurice, Helmer Catherine, Portet Florence, Amouyel Philippe, Lathrop Mark, Elbaz Alexis, Durr Alexandra, Martinez Maria, Brice Alexis

Abstract excerpt

We performed a three-stage genome-wide association study (GWAS) to identify common Parkinson's disease (PD) risk variants in the European population. The initial genome-wide scan was conducted in a French sample of 1039 cases and 1984 controls, using almost 500 000 single nucleotide polymorphisms...

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Identifiers

PMID: 21084426
DOI: 10.1093/hmg/ddq497

Genes

BST1
SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21084426-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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