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Article

In humans IL‐6 is released from the brain during and after exercise and paralleled by enhanced IL‐6 mRNA expression in the hippocampus of mice

16 Nov 2010

Abstract excerpt

AIM: Plasma interleukin-6 (IL-6) increases during exercise by release from active muscles and during prolonged exercise also from the brain. The IL-6 release from muscles continues into recovery and we tested whether the brain also releases IL-6 in recovery from prolonged exercise in humans. Additionally, it was evaluated in mice whether brain release of IL-6 reflected enhanced IL-6 mRNA expression in the brain...

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PMID: 21083649
DOI: 10.1111/j.1748-1716.2010.02223.x

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