Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagic-lysosomal pathway functions in the masseter and tongue muscles in the klotho mouse, a mouse model for aging.

Molecular and cellular biochemistry - 1 Feb 2011

Iida Ryo-hei, Kanko Syuhei, Suga Takeo, Morito Mitsuhiko, Yamane Akira

Abstract excerpt

Klotho mutant (kl/kl) mice, a type of short-lived mouse models, display several aging-related phenotypes. To investigate whether the atrophy of skeletal muscles is induced in these mice via activation of the ubiquitin-proteasomal pathway and/or the autophagic-lysosomal pathway through an alterati...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrophy
Share to Eukaryotic Initiation Factors
Share to Glucuronidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor I

Share to Klotho Proteins

Share to Ribosomal Protein S6 Kinases, 70-kDa

Share to Tongue

Share to Ubiquitin

Source

Identifiers

PMID: 21082218
DOI: 10.1007/s11010-010-0642-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21082218-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagic-lysosomal pathway functions in the masseter and tongue muscles in the klotho mouse, a mouse model for aging.PMID 21082218Read ↗

Klotho: a fundamental regulator of aging.Semantic proximity Read ↗

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulationSemantic proximity Read ↗

Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophySemantic proximity Read ↗

Ubiquitin Ligases in Longevity and Aging Skeletal MuscleSemantic proximity Read ↗

Toward a better understanding of Klotho.Semantic proximity Read ↗

Klotho an Autophagy Stimulator as a Potential Therapeutic Target for Alzheimer’s Disease: A ReviewSemantic proximity Read ↗

Autophagy is Impaired in the Tibialis Anterior of Dystrophin Null MiceSemantic proximity Read ↗

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasomeSemantic proximity Read ↗

DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice.Semantic proximity Read ↗

Suppression of Aging in Mice by the Hormone KlothoSemantic proximity Read ↗

Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass declineSemantic proximity Read ↗

Long-lived Klotho mice: new insights into the roles of IGF-1 and insulin in agingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.