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Ubiquitin Ligases in Longevity and Aging Skeletal Muscle

9 Jul 2022

Abstract excerpt

The development and prevalence of diseases associated with aging presents a global health burden on society. One hallmark of aging is the loss of proteostasis which is caused in part by alterations to the ubiquitin-proteasome system (UPS) and lysosome-autophagy system leading to impaired function and maintenance of mass in tissues such as skeletal muscle. In the instance of skeletal muscle, the impairment of...

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PMID: 35886949
DOI: 10.3390/ijms23147602

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