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Article

Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors.

Journal of experimental & clinical cancer research : CR - 16 Nov 2010

Blish Kimberly R, Clausen Kathryn A, Hawkins Gregory A, Garvin A Julian, Willingham Mark C, Turner Julie C, Torti Frank M, Torti Suzy V

Abstract excerpt

BACKGROUND: Deletions within the short arm of chromosome 7 are observed in approximately 25% of adult and 10% of Wilms pediatric renal tumors. Within Wilms tumors, the region of interest has been delineated to a 2-Mb minimal region that includes ten known genes. Two of these ten candidate genes, SOSTDC1 and MEOX2, are particularly relevant to tumor development and maintenance. This finding, coupled with evidence...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21080955
DOI: 10.1186/1756-9966-29-147
PMCID: PMC3002326

Genes

SOSTDC1
MEOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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