Article
Isolation and characterization of human apolipoprotein A-I Fukuoka (110 Glu----Lys). A novel apolipoprotein variant.
Biochimica et biophysica acta - 2 Apr 1990
Takada Y, Sasaki J, Ogata S, Nakanishi T, Ikehara Y, Arakawa K
Abstract excerpt
A novel genetic variant of apolipoprotein(apo) A-I Fukuoka, has been identified in a Japanese family. This variant has a relative charge of +2 compared to normal apolipoprotein A-I (A-I4), on the isoelectric focusing gels and the same molecular mass and immunologic characteristics as normal apolipoprotein A-I. This variant, transmitted as an autosomal co-dominant inheritance was purified by preparative Immobiline...
Topics
- Amino Acid Sequence
- Apolipoprotein A-I
- Apolipoproteins A
- Base Sequence
- Genetic Variation
- Humans
- Isoelectric Focusing
- Lipid Metabolism, Inborn Errors
- Lipoproteins, HDL
- Male
- Middle Aged