Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular basis of complement factor I (CFI) polymorphism: one of two polymorphic suballeles responsible for CFI A is Japanese-specific.

Journal of human genetics - 1 Jan 2008

Yuasa Isao, Nakagawa Mayumi, Umetsu Kazuo, Harihara Shinji, Matsusue Aya, Nishimukai Hiroaki, Fukumori Yasuo, Saitou Naruya, Park Kyung Sook, Jin Feng, Lucotte Gérard, Chattopadhyay Prasanta K, Henke Lotte, Henke Jürgen

Abstract excerpt

Isoelectric focusing has revealed that human complement factor I (CFI) is controlled by two polymorphic alleles, CFI(*)A and CFI(*)B, and a few rare variant alleles. In this study the molecular basis of the CFI polymorphism was investigated in 174 Japanese. The CFI(*)A was divided into two suballeles, CFI(*)As (R201S) and CFI(*)Ah (R406H). CFI(*)Aj, a rare variant allele originating from CFI(*)Ah, had an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Complement Factor I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CFI gene

Share to Genetics, Population

Share to Haplotypes

Share to Mutation

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18825487
DOI: 10.1007/s10038-008-0337-4

Genes

CFI

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular basis of complement factor I (CFI) polymorphism: one of two polymorphic suballeles responsible for CFI A is Japanese-specific.PMID 18825487Read ↗

Allele frequencies of human complement factor I in a sample from Iwate, northern Japan, with the description of geographical cline.Semantic proximity Read ↗

A hypervariable STR polymorphism in the complement factor I (CFI) gene: Asian-specific alleles.Semantic proximity Read ↗

CFI-rs7356506 polymorphisms associated with Vogt-Koyanagi-Harada syndrome.Semantic proximity Read ↗

Genetic polymorphism of complement component C6, C7 and C8(1) in Chinese Han population in northeast China.Semantic proximity Read ↗

A hypervariable STR polymorphism in the CFI gene: southern origin of East Asian-specific group H alleles.Semantic proximity Read ↗

Polymorphism of complement factor I: population study in Japanese and phenotyping in bloodstains.Semantic proximity Read ↗

C1R subcomponent polymorphism in Japanese: description of a new allele.Semantic proximity Read ↗

Genetic polymorphism of human complement factor I (C3b inactivator) in the Chinese Han population.Semantic proximity Read ↗

Factor I (IF) polymorphism in the Japanese population: existence of a new variant and quantitative analysis of different allotypes.Semantic proximity Read ↗

Polymorphisms of complement component I and C1R subcomponent of C1 in nine aboriginal Taiwanese populations.Semantic proximity Read ↗

Study of HLA class I, class II and complement genes (C2, C4A, C4B and BF) in Japanese psoriatics and analysis of a newly-found high-risk haplotype by pulsed field gel electrophoresis.Semantic proximity Read ↗

Polymorphism of complement component I in Mongoloid populations: a new genetic variant IF A2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.