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Article

Mechano-Transduction: From Molecules to Tissues

18 Nov 2014

Abstract excerpt

External forces play complex roles in cell organization, fate, and homeostasis. Changes in these forces, or how cells respond to them, can result in abnormal embryonic development and diseases in adults. How cells sense and respond to these mechanical stimuli requires an understanding of the biophysical principles that underlie changes in protein conformation and result in alterations in the organization and...

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PMID: 25405923
DOI: 10.1371/journal.pbio.1001996

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