Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathogenic mutations in antisense mitochondrial tRNAs.

Journal of theoretical biology - 21 Jan 2011

Seligmann Hervé

Abstract excerpt

Pathogenic mutations in mitochondrial tRNAs are 6.5 times more frequent than in other mitochondrial genes. This suggests that tRNA mutations perturb more than one function. A potential additional tRNA gene function is that of templating for antisense tRNAs. Pathogenic mutations weaken cloverleaf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticodon
Share to Chi-Square Distribution
Share to Genome, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Regression Analysis

Share to RNA, Antisense

Share to RNA, Mitochondrial

Share to RNA, Transfer

Share to RNA, Transfer, Ser

Source

Identifiers

PMID: 21073883
DOI: 10.1016/j.jtbi.2010.11.007

Genes

UCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21073883-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathogenic mutations in antisense mitochondrial tRNAs.PMID 21073883Read ↗

Undetected antisense tRNAs in mitochondrial genomes?Semantic proximity Read ↗

Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility.Semantic proximity Read ↗

Assigning pathogenicity to mitochondrial tRNA mutations: when "definitely maybe" is not good enough.Semantic proximity Read ↗

Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3' end processing efficiency in vitro.Semantic proximity Read ↗

Pathogenic human mitochondrial tRNA variants impair RNA processing by compromising 5′ leader removalSemantic proximity Read ↗

Impact of disease-related mitochondrial mutations on tRNA structure and function.Semantic proximity Read ↗

Disease associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation and tRNA processing by mtRNase PSemantic proximity Read ↗

Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation, and tRNA processing by mtRNase P.Semantic proximity Read ↗

Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants.Semantic proximity Read ↗

Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavageSemantic proximity Read ↗

Prediction of pathogenic mutations in mitochondrially encoded human tRNAs.Semantic proximity Read ↗

Pathogenesis-related mutations in the T-loops of human mitochondrial tRNAs affect 3' end processing and tRNA structure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.