Article
Undetected antisense tRNAs in mitochondrial genomes?
Biology direct - 16 Jun 2010
Seligmann Hervé
Abstract excerpt
BACKGROUND: The hypothesis that both mitochondrial (mt) complementary DNA strands of tRNA genes code for tRNAs (sense-antisense coding) is explored. This could explain why mt tRNA mutations are 6.5 times more frequently pathogenic than in other mt sequences. Antisense tRNA expression is plausible because tRNA punctuation signals mt sense RNA maturation: both sense and antisense tRNAs form secondary structures...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
