Article
COMT Val158Met-stress interaction in psychosis: role of background psychosis risk.
CNS neuroscience & therapeutics - 1 Dec 2011
Collip Dina, van Winkel Ruud, Peerbooms Odette, Lataster Tineke, Thewissen Viviane, Lardinois Marielle, Drukker Marjan, Rutten Bart P F, Van Os Jim, Myin-Germeys Inez
Abstract excerpt
BACKGROUND: The interplay between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and environmental stress may have etiological relevance for psychosis, but differential effects have been reported in healthy control and patient groups, suggesting that COMT Val158Met interactions with stress may be conditional on background genetic risk for psychotic disorder. METHODS: Patients with a nonaffective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.