Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subtle gene-environment interactions driving paranoia in daily life.

Genes, brain, and behavior - 1 Feb 2009

Simons C J P, Wichers M, Derom C, Thiery E, Myin-Germeys I, Krabbendam L, van Os J

Abstract excerpt

It has been suggested that genes impact on the degree to which minor daily stressors cause variation in the intensity of subtle paranoid experiences. The objective of the present study was to test the hypothesis that catechol-O-methyltransferase (COMT) Val(158)Met and brain-derived neurotrophic factor (BDNF) Val(66)Met in part mediate genetic effects on paranoid reactivity to minor stressors. In a general...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Catechol O-Methyltransferase
Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Environment

Share to Social Environment

Share to Stress, Psychological

Share to Young Adult

Source

Identifiers

PMID: 18721261
DOI: 10.1111/j.1601-183X.2008.00434.x

Genes

BDNF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subtle gene-environment interactions driving paranoia in daily life.PMID 18721261Read ↗

COMT Val158Met-stress interaction in psychosis: role of background psychosis risk.Semantic proximity Read ↗

Genes making one feel blue in the flow of daily life: a momentary assessment study of gene-stress interaction.Semantic proximity Read ↗

Emotional reactivity to daily life stress in psychosis.Semantic proximity Read ↗

The role of stress-regulation genes in moderating the association of stress and daily-life psychotic experiences.Semantic proximity Read ↗

Association between stressful life events and psychotic experiences in adolescence: Evidence for gene–environment correlationsSemantic proximity Read ↗

The psychology of psychiatric genetics: evidence that positive emotions in females moderate genetic sensitivity to social stress associated with the BDNF Val-sup-6-sup-6Met polymorphism.Semantic proximity Read ↗

Catechol-O-Methyltransferase moderates effect of stress mindset on affect and cognition.Semantic proximity Read ↗

Stress, COMT Polymorphisms, and Depressive Symptoms in Older Australian Women: An Exploratory Study.Semantic proximity Read ↗

Genetics of emotion.Semantic proximity Read ↗

Personality Pathology and Momentary Stress ProcessesSemantic proximity Read ↗

COMT Val158Met moderation of stress-induced psychosis.Semantic proximity Read ↗

From epidemiology to daily life: linking daily life stress reactivity to persistence of psychotic experiences in a longitudinal general population study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.