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Article

Afamelanotide, an agonistic analog of α-melanocyte-stimulating hormone, in dermal phototoxicity of erythropoietic protoporphyria

13 Nov 2010

Abstract excerpt

IMPORTANCE OF THE FIELD: Afamelanotide, an α-melanocyte stimulating hormone (MSH) agonistic analog is a first-in-class therapeutic. Its application to protoporphyria (PP), a disease associated with absolute sunlight-intolerance is discussed. AREAS COVERED IN THIS REVIEW: The genetics and existing therapy of the inherited disease PP comprising both erythropoietic protoporphyria and X-linked dominant...

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PMID: 21073357
DOI: 10.1517/13543784.2010.535515

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