Article
Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2011
He Jing, Wilkens Lynne R, Stram Daniel O, Kolonel Laurence N, Henderson Brian E, Wu Anna H, Le Marchand Loic, Haiman Christopher A
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) in populations of European ancestry have identified several loci that confer an increased risk of colorectal cancer (CRC). METHODS: We studied the generalizability of the associations with 11 risk variants for CRC on 8q23 (rs16892766), 8q24 (rs6983267), 9p24 (rs719725), 10p14 (rs10795668), 11q23 (rs3802842), 14q22 (), 15q13 (), 16q22...