Article
Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression.
Clinical and vaccine immunology : CVI - 1 Jan 2011
Yu Jae-Sung, Whitesides John, Lee Sun-Hee, Taylor Natalie, Jacobs William R, Letvin Norman L, Haynes Barton F
Abstract excerpt
Recombinant mycobacteria hold promise as vectors for delivery of HIV-1 and other pathogen antigen inserts for inducing systemic and mucosal immune responses. In general, the immunogenicity of the recombinant mycobacterial insert is proportional to the level of insert expression. In this study, a...
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