Article
A novel method for the genome-wide high resolution analysis of DNA damage.
Nucleic acids research - 1 Jan 2011
Teng Yumin, Bennett Mark, Evans Katie E, Zhuang-Jackson Huayun, Higgs Andy, Reed Simon H, Waters Raymond
Abstract excerpt
DNA damage occurs via endogenous and exogenous genotoxic agents and compromises a genome's integrity. Knowing where damage occurs within a genome is crucial to understanding the repair mechanisms which protect this integrity. This paper describes a new development based on microarray technology which uses ultraviolet light induced DNA damage as a paradigm to determine the position and frequency of DNA damage and...
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